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HRID2180766

反应详情

EQUATION

反应方程式

HRID 2180766 的结构方程式

REACTANTS

反应物

2
结构：C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O
HCID12135350

N-[(3,5-difluorophenyl)acetyl]alanine

C11H11F2NO3

结构：COC(=O)[C@@H](N)Cc1c[nH]cn1.Cl.Cl
HCID178419105

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1
HCID178501428

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO.ClCCl
溶剂HCID21226129

未命名化合物

PROCEDURE

实验过程

Following General Procedure A and using N-(3,5-difluorophenylacetyl)-L-alanine (from Example B2) and L-histidine methyl ester dihydrochloride (Sigma), the title compound was prepared as a solid (mp=195-197° C.). The reaction was monitored by tlc (Rf=0.29 in 10% CH3OH/CH2Cl2).