Morpholine → HCID 22894831, compound

Participants

Reaction Steps

Following General Procedure C and using N-(3-nitrophenylacetyl)-L-alanine (from Example DlI above) and 4-(L-valinyl)morpholine (prepared from N-BOC-L-valine (Aldrich) and morpholine (Aldrich) using General Procedure M, followed by removal of the BOC-group using General Procedure P), the title compound was prepared as a solid. The reaction was monitored by tlc (Rf=0.5 in 9:1 CHCl3/MeOH) and the product was purified by silica gel chromatography using 98:2 CHCl3/MeOH as the eluent.

Provenance & Evidence