Hydrazine → 6-(N-methylpiperazinyl)hexylamine

HRID 21809Notes

Reaction equation

HRID 21809 reaction equation
[NH2:1]N.[CH3:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH:5]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]C1C=CC=C2C(NC(=O)C=12)=O>CO>[CH3:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH:5]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][NH2:1]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 544966336-(N-methylpiperazinyl)hexylphthalimide

Product 1

HCID 537642486-(N-methylpiperazinyl)hexylamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 6-(N-methylpiperazinyl)hexylphthalimide (263 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-2e3f5305c67a492683d0a57266c4ce8a
Source dataset
uspto-grants-1995_06
Patent number
US05424451

Reaction notes

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