反应详情

Tolterodine tartrate (2.1 g) is mixed with water (45 ml) and toluene (2.5 ml). Sodium carbonate (800 mg) is added to the slurry. Sodium hydroxide (2.0 N, 1.5 ml) is added. The mixture is extracted three times with toluene (3 ml), saving the organic phase. Anhydrous potassium carbonate is added to the organic phase dissolve the tolterodine tartate, giving the title compound in solution.

1. extractionThe mixture is extracted three times with toluene (3 ml)
2. additionAnhydrous potassium carbonate is added to the organic phase
3. dissolutiondissolve the tolterodine tartate