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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 21810Generated: October 26, 2026

1-Methylpiperazine → 8-(N-methylpiperazinyl)octylphthalimide

https://huagongshe.com/reaction/21810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant8-BromooctylphthalimideHCID 23290643—
SolventDiethyl EtherHCID 3283—
Product8-(N-methylpiperazinyl)octylphthalimideHCID 53803168—

Reaction Steps

8-Bromooctylphthalimide (516 mg; 2.0 mmoles) and N-methylpiperazine (0.44 ml; 4.0 mmoles) were dissolved in anhydrous ethyl ether (5 ml). Reaction times and process as per Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05424451
Source datasetuspto-grants-1995_06
ORD IDord-8c90f546436341d5ac303db8badeae41
Source noteuspto-grants-1995_06