HCID 22485636, compound → HCID 73855572, compound

Participants

Reaction Steps

Reaction of (2,2-dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-acetyl chloride with N-[bis-(4-fluoro-phenyl)-methyl]-O-methyl-hydroxylamine as described in the preparation of compound 1-C gave the title amide as white crystals (88% yield): mp 137° C. (ethyl acetate-hexane). 1HNMR 400 MHz (CDCl3) δ (ppm): 1.74 (6H, s, CH3), 3.26 (3H, s, OCH3), 6.42 (1H, s, CH), 6.81 (1H, s, CH), 7.03 (4H, m, aromatics), 7.28 (4H, m, aromatics). Anal. calcd for C21H19F2NO5: C, 62.53; H, 4.75; N, 3.47. Found: C, 62.49; H, 4.66; N, 3.35.

Provenance & Evidence