Methanesulfonamide → HCID 72613076, compound

Participants

Reaction Steps

Reaction of N-[1-(4-chlorobenzyl)-2-(4-chlorophenyl)-ethyl]-2-(2,2-dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-N-methyl-acetamide (0.363 g, 0.81 mmol) with methanesulfonamide (0.077 g, 0.81 mmol) as described in the preparation of compound 22 gave 0.284 g (72% yield) of the title amide as a white solid. 1H NMR (400 MHz, DMSO) δ: mixture of rotamers: 2.5-3.5 (10H, m, CH3 and CH2), 4.55 and 5.1 (1H, broad m, CH), 5.8 (1H, s, CH), 7.1-7.4 (8H, m, aromatics).

Provenance & Evidence