HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-5-methyl-2-phenyl-1,3-oxazole → (S)-2-Ethoxy-3-[1-(5-methyl-2-phenyl-oxazol-4-ylmethyl)-1H-indol-5-yl]-propionic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-5-methyl-2-phenyl-1,3-oxazole | HCID 9794289 | — |
| Reactant | (S)-2-ethoxy-3-(1H-indol-5-yl)-propionic acid methyl ester | HCID 69563912 | — |
| Product | (S)-2-Ethoxy-3-[1-(5-methyl-2-phenyl-oxazol-4-ylmethyl)-1H-indol-5-yl]-propionic Acid | HCID 10431329 | 64% |
Reaction Steps
Starting from (S)-2-ethoxy-3-(1H-indol-5-yl)-propionic acid methyl ester and 4-chloromethyl-2-phenyl-5-methyl-oxazole, the title compound was obtained in 64% yield as a colourless oil. MS: (M−H)− 403.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06890947B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-f93aa688f27e411c889ac9688c408a9f |
| Source note | uspto-grants-2005_05 |