HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-2-(4-ethylphenyl)-5-methyl-1,3-oxazole → 2-ethoxy-3-(1-((2-(4-ethylphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-2-(4-ethylphenyl)-5-methyl-1,3-oxazole | HCID 16003033 | — |
| Reactant | Rac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl ester | HCID 69563293 | — |
| Product | 2-ethoxy-3-(1-((2-(4-ethylphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid | HCID 10342769 | 41% |
Reaction Steps
Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-(4-ethyl-phenyl)-5-methyl-oxazole, the title compound was obtained in 41% yield as a yellow solid. MS: (M+H)+ 433.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06890947B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-d4b4b47cdbde4862b71e2bc1c19df195 |
| Source note | uspto-grants-2005_05 |