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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181217Generated: November 2, 2026

4-Chloromethyl-2-(3,5-difluorophenyl)-5-methyloxazole → HCID 10365954, compound

https://huagongshe.com/reaction/2181217

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloromethyl-2-(3,5-difluorophenyl)-5-methyloxazoleHCID 22485701—
ReactantRac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl esterHCID 69563293—
ProductHCID 10365954HCID 1036595420%

Reaction Steps

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-(3,5-difluoro-phenyl)-5-methyl-oxazole, the title compound was obtained in 20% yield as a brown oil. MS: (M+H)+ 441.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-0300f80a94b44303a258e664e0de8876
Source noteuspto-grants-2005_05