HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-2-(3,5-dichlorophenyl)-5-methyl-1,3-oxazole → 1-[[2-(3,5-Dichlorophenyl)-5-methyl-4-oxazolyl]methyl]-α-ethoxy-1H-indole-5-propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-2-(3,5-dichlorophenyl)-5-methyl-1,3-oxazole | HCID 22273912 | — |
| Reactant | Rac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl ester | HCID 69563293 | — |
| Product | 1-[[2-(3,5-Dichlorophenyl)-5-methyl-4-oxazolyl]methyl]-α-ethoxy-1H-indole-5-propanoic acid | HCID 10344769 | 4% |
Reaction Steps
Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-(3,5-dichloro-phenyl)-5-methyl-oxazole, the title compound was obtained in 4% yield as a pale yellow solid. MS: (M+H)+ 473.1 and 475.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06890947B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-a4a39a8c31eb4d49b343815b3dd1c43e |
| Source note | uspto-grants-2005_05 |