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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181219Generated: November 1, 2026

4-Chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazole → HCID 10320822, compound

https://huagongshe.com/reaction/2181219

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazoleHCID 21974259—
ReactantRac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl esterHCID 69563293—
ProductHCID 10320822HCID 1032082248%

Reaction Steps

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazole, the title compound was obtained in 48% yield as a colourless solid. MS: (M+H)+ 437.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-9d01550560104c08b7450f9611f35bc5
Source noteuspto-grants-2005_05