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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181221Generated: October 29, 2026

4-(Chloromethyl)-5-methyl-2-(thiophen-2-yl)-1,3-oxazole → HCID 10409296, compound

https://huagongshe.com/reaction/2181221

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-5-methyl-2-(thiophen-2-yl)-1,3-oxazoleHCID 5076491—
ReactantRac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl esterHCID 69563293—
ProductHCID 10409296HCID 1040929631%

Reaction Steps

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-5-methyl-2-thiophen-2-yl-oxazole, the title compound was obtained in 31% yield as a yellow solid. MS: (M+H)+ 411.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-c1918ef8faa9429fbf6ae19279c27a7e
Source noteuspto-grants-2005_05