HCID 9881828, compound → HCID 10342094, compound

HRID 2181225Notes

Reaction equation

HRID 2181225 reaction equation
C([O:3][C:4](=[O:19])[CH:5]([O:16][CH2:17][CH3:18])[CH2:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[NH:12][CH:11]=[CH:10]2)C.Br[CH2:21][C:22]1[N:23]=[C:24]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[S:25][C:26]=1[CH3:27]>>[CH2:17]([O:16][CH:5]([CH2:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH2:21][C:22]1[N:23]=[C:24]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[S:25][C:26]=1[CH3:27])[CH:11]=[CH:10]2)[C:4]([OH:3])=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 9881828HCID 9881828, compoundHCID 69563293Rac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl ester

Product 1

HCID 10342094HCID 10342094, compoundYield 1%

Procedure

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-bromomethyl-5-methyl-2-phenyl-thiazole, the title compound was obtained in 1% yield as a yellow oil. MS: (M+H)+ 421.2.

Sources & evidence

ORD record
ord-4378e6614a0448aaa689ebef2213db75
Source dataset
uspto-grants-2005_05
Patent number
US06890947B2

Reaction notes

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