HCID 10341046, compound → HCID 10250642, compound

Participants

Reaction Steps

A suspension of 9 mg of (Z)-2-Methoxy-3-{1-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethyl]-1H-indol-5-yl}-acrylic acid in 2 ml of methanol and 1 ml of dichloromethane and 6 mg of Pd/C 10%) was hydrogenated at 22° C. and 1 bar until hydrogen uptake ceased (2 h). The mixture was filtered, the filtrate evaporated and the residue was purified by HPLC (RP-18, CH3CN/H2O, gradient) to give 7 mg of the title compound as a colorless oil. MS: (M−H)− 403.3.

Provenance & Evidence