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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181244Generated: November 1, 2026

4-(Chloromethyl)-5-methyl-2-(2-methylphenyl)-1,3-oxazole → HCID 10094344, compound

https://huagongshe.com/reaction/2181244

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-5-methyl-2-(2-methylphenyl)-1,3-oxazoleHCID 21974258—
ReactantHCID 69562886HCID 69562886—
ProductHCID 10094344HCID 10094344—

Reaction Steps

In analogy to the procedure described in example 44, rac-3-(1H-indol-5-yl)-2-isopropoxy-propionic acid methyl ester (preparation 8) was reacted with 4-chloromethyl-5-methyl-2-o-tolyl-oxazole to give rac-2-isopropoxy-3-[1-(5-methyl-2-o-tolyl-oxazol-4-ylmethyl)-1H-indol-5-yl]-propionic acid as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-4498b961a2ed4e11ae56b7d0b1268e9d
Source noteuspto-grants-2005_05