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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181246Generated: November 1, 2026

2-(4-Trifluoromethylphenyl)-4-chloromethyl-5-methyloxazole → HCID 10096908, compound

https://huagongshe.com/reaction/2181246

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Trifluoromethylphenyl)-4-chloromethyl-5-methyloxazoleHCID 10236333—
ReactantHCID 69562886HCID 69562886—
ProductHCID 10096908HCID 10096908—

Reaction Steps

In analogy to the procedure described in example 44, rac-3-(1H-indol-5-yl)-2-isopropoxy-propionic acid methyl ester (preparation 8) was reacted with 4-chloromethyl-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole to give rac-2-isopropoxy-3-{1-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethyl]-1H-indol-5-yl}-propionic acid as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-cf71d297c2c44dda86df1e8f7d14a66f
Source noteuspto-grants-2005_05