4-(Chloromethyl)-2-(2-chlorophenyl)-5-methyloxazole → Rac-2-but-3-enyloxy-3-{1-[2-(2-chloro-phenyl)-5-methyl-oxazol-4-ylmethyl]-1h-indol-5-yl}-propionic acid

Participants

Reaction Steps

In analogy to the procedure described in example 44, rac-2-but-3-enyloxy-3-(1H-indol-5-yl)-propionic acid methyl ester (preparation 9) was reacted with 4-chloromethyl-2-(2-chloro-phenyl)-5-methyl-oxazole to give rac-2-but-3-enyloxy-3-{1-[2-(2-chloro-phenyl)-5-methyl-oxazol-4-ylmethyl]-1H-indol-5-yl}-propionic acid as light yellow solid.

Provenance & Evidence