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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181253Generated: October 25, 2026

2-(4-Trifluoromethylphenyl)-4-chloromethyl-5-methyloxazole → HCID 10413122, compound

https://huagongshe.com/reaction/2181253

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Trifluoromethylphenyl)-4-chloromethyl-5-methyloxazoleHCID 10236333—
ReactantRac-2-ethoxy-3-(4-methyl-1h-indol-5-yl)-propionic acid ethyl esterHCID 69563695—
ProductHCID 10413122HCID 10413122—

Reaction Steps

In analogy to the procedure described in example 44, rac-2-ethoxy-3-(4-methyl-1H-indol-5-yl)-propionic acid ethyl ester [preparation 10h)] was reacted with 4-chloromethyl-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole to give rac-2-ethoxy-3-{4-methyl-1-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethyl]-1H-indol-5-yl}-propionic acid as yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-b363d9a228c64352af32a8f75dbd03e5
Source noteuspto-grants-2005_05