Ammonia → HCID 22485770, compound

Participants

Reaction Steps

The ester of Example 38 (40 mg, 0.07 mmol) in ethanol (1.5 ml) was treated with NH3 (1 ml of 25% aqueous solution). The reaction mixture was stirred at ambient temperature for 2 h and evaporated to give a residue (40 mg) which was purified using preparative plate thin layer chromatography eluting with ethyl acetate:hexane 2:1 to yield the desired product (10 mg).

Provenance & Evidence