Methanesulfonic Acid → HCID 22485566, compound

Participants

Reaction Steps

To a solution of N,N′-bis[2-[4-(2-methoxyethoxy)-3,5-dimethoxyphenyl]-5-pyridyl]-N,N′-dimethylethylenediamine (139.0 mg, 0.21 mmol) in methanol (2.0 mL) was added a 1.0 M aqueous methanesulfonic acid solution (0.42 mL, 0.42 mmol) was added, and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue, and the mixture was concentrated under reduced pressure. The residue was recrystallized from methanol-diethyl ether to afford the title compound as a yellow crystalline powder (melting point: 211.0-214.0° C. ) (127.0 mg, yield: 71%).

Provenance & Evidence