Methanesulfonic Acid → HCID 87796412, compound

Participants

Reaction Steps

To a solution of N,N′-bis[2-(4-fluoro-3,5-dimethoxy-phenyl)-5-pyridyl]-N,N′-dimethylethylenediamine (150.0 mg, 0.270 mmol) in chloroform (30 mL) was added a 1.0 M aqueous methanesulfonic acid solution (0.60 mL, 0.60 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue, and the mixture was concentrated under reduced pressure. Diethyl ether was added to the residue and the resulting precipitate was collected by filtration to yield the title compound as a yellow crystalline powder (melting point:≧300.0° C.)(1 81.0 mg, yield: 90%).

Provenance & Evidence