Methanesulfonic Acid → HCID 22485476, compound

Participants

Reaction Steps

To a solution of bis[N-[2-(3,4,5-trimethoxyphenyl)-5-pyridyl]-2-aminoethyl]ether (53.1 mg, 0.0900 mmol) in ethanol (5.0 mL) was added a 1.0 M aqueous methanesulfonic acid solution (0.20 mL, 0.20 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (10 mL) was added to the residue, and the mixture was concentrated under reduced pressure. The residue was suspended in ethanol-diethyl ether and the resulting precipitate was collected by filtration to provide the title compound as a pale brown amorphous powder (49.9 mg, yield: 71%).

Provenance & Evidence