Methanesulfonic Acid → HCID 22485471, compound

Participants

Reaction Steps

To a solution of N,N′-bis[2-(3,4,5-trimethoxyphenyl)-5-pyridyl]-N,N′-dimethyl-1,6-hexanediamine (243.0 mg, 0.370 mmol) in methanol-methylene chloride (6:1, 3.5 mL) was added a 1.0 M aqueous methanesulfonic acid (0.76 mL, 0.76 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue, and the mixture was concentrated under reduced pressure. The residue was recrystallized from methanol-diethyl ether to yield the title compound as yellow needles (melting point: 192.0-195.0° C.) (251.0 mg, yield: 81%).

Provenance & Evidence