Methanesulfonic Acid → HCID 135800893, compound

Participants

Reaction Steps

To a solution of N,N′-bis[2-(4-hydroxy-3,5-dimethoxyphenyl)-5-pyridyl]-N,N′-dimethyl-1,3-propanediamine (43.0 mg, 0.076 mmol) in methanol-chloroform (1:2, 3.0 mL) was added a 1.0 M aqueous methanesulfonic acid (0.16 mL, 0.16 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue, and the mixture was concentrated under reduced pressure. The residue was recrystallized from ethanol-diethyl ether to provide the title compound as a yellow crystalline powder (melting point: 198.0-202.0° C.)(17.0 mg, yield: 30%).

Provenance & Evidence