Water → HCID 22484119, compound

Participants

Reaction Conditions

Reaction Steps

The product of step b) (6.65 g) was dissolved in tetrahydrofuran (200 mls) and LiA1H(OtBu)3 (43 mls, 1M in tetrahydrofuran) was added. The reaction mixture was heated at 60° C. for 18 hrs. Water was then added and the reaction mixture was concentrated to dryness in vacuo. The residue was extracted into ethyl acetate and the solution was dried over magnesium sulphate, filtered, and concentrated in vacuo to a greenish solid which was ultrasonicated in isohexanes for 3 hrs before being collected via filtration to yield 2.76 g of the subtitle compound as a green solid.

Provenance & Evidence