Ammonium Hydroxide → HCID 22481877, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of (±)-α-(4-amino-2,6-dichlorophenyl)-2-pyridineacetonitrile (0.324 mol) in H2SO4 90% (900 ml) was stirred at 90° C. for 2 hours, then poured out on ice and basified with a concentrated NH4OH solution. The precipitate was filtered off, washed with H2O and centrifuged. The residue was dried, yielding 86.0 g (90%) of (±)-α-(4-amino-2,6-dichlorophenyl)-2-pyridineacetamide (interm. 43).

Provenance & Evidence