HCID 53322744, compound → HCID 13945489, compound

HRID 2181718Notes

Reaction equation

HRID 2181718 reaction equation
[CH3:1][C:2]1([CH3:26])[C@H:7]2[CH2:8][C@@H:9]3[O:21][CH:22]([O:23]C)[C@@:6]2([C@@H:11]2[CH2:12][CH2:13][C@H:14]4[C:17]([C:19](=[O:20])[C@@:10]32[C@@H:15]4[OH:16])=[CH2:18])[C@@H:5]([OH:25])[CH2:4][CH2:3]1>CCCCCC.C(OC(=O)C)C>[CH3:1][C:2]1([CH3:26])[C@H:7]2[CH2:8][C@@H:9]([OH:21])[C@@:10]34[C:19](=[O:20])[C:17](=[CH2:18])[C@@H:14]([C@H:15]3[OH:16])[CH2:13][CH2:12][C@H:11]4[C@:6]2([CH2:22][OH:23])[C@@H:5]([OH:25])[CH2:4][CH2:3]1

Participants

3

Reactant 1

HCID 53322744HCID 53322744, compound

Product 1

HCID 13945489HCID 13945489, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The third fraction obtained by the first silica gel column chromatography was loaded on the third silica gel column chromatography, and four fractions, 3-A, 3-B, 3-C and 3-D, were obtained by elution with hexane-ethylacetate step gradient system. Kamebacetal A represented by Chemical Formula 2 was isolated from the 3-B fraction, and kamebakaurin represented by Chemical Formula 3 was isolated from the 3-C fraction.

Workup

  1. customThe third fraction obtained by the first silica gel column chromatography

Sources & evidence

ORD record
ord-65ab038b840342ebb359cfa1a074e25c
Source dataset
uspto-grants-2005_05
Patent number
US06894073B2

Reaction notes

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