Methanol → HCID 86593944, compound

Participants

Reaction Steps

Acetyl chloride (2 mL) was added drop-wise over a period of 5 min to methanol (25 mL) maintained in an ice-bath. m-Xylylenediammonium galactarate (14, 1.008 g, 2.910 mmol) was then to the solution and the reaction was allowed to reflux for 4 h. Within 1 h complete dissolution had occurred. The solvent was removed under reduced pressure and the remaining white powder dried under vacuum at room temperature for 16 h to give white solid 1:1 dimethyl galactarate/m-xylylenediammonium dichloride (20, 1.158 g, 2.588 mmol, 88.94%).

Provenance & Evidence