Dichloromethane → HCID 10070335, compound

Participants

Reaction Steps

The title compound was prepared from (R)-5-[(4-methoxyphenyl)sulfonyl]-6-phenyl-5,6-dihydrophenanthridine* (1.35 g, 3.16 mmol), cyclohexene (6.16 g, 75 mmol), and 1.0 M boron tribromide in dichloromethane (20 mL, 20 mmol) according to the procedure and in the same manner as described in Example 1, step b; and yielded, after chromatographic purification and crystallization from diethyl ether-hexane, 4-{[(R)-6-phenylphenanthridin-5(6H)-yl]sulfonyl}phenol* (0.691 g, 1.67 mmol, 53%) as a homogeneous, colorless, crystalline, single enantiomer*, m.p. 208-210° C.;

Provenance & Evidence