HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenanthridine → 6-Ethyl-5-[(4-methoxy-3-methylphenyl)sulfonyl]-5,6-dihydrophenanthridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenanthridine | HCID 9189 | — |
| Reactant | 4-Methoxy-3-methylbenzene-1-sulfonyl chloride | HCID 15915317 | — |
| Reactant | HCID 178506846 | HCID 178506846 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 6-Ethyl-5-[(4-methoxy-3-methylphenyl)sulfonyl]-5,6-dihydrophenanthridine | HCID 22482303 | — |
Reaction Steps
The title compound was prepared from phenanthridine, 0.62 M ethyllithium in diethyl ether, and 4-methoxy-3-methylbenzenesulfonyl chloride according to the procedure and in the same manner as described in Example 18, step a and yielded, after chromatographic purification and crystallization from diethyl ether, 6-ethyl-5-[(4-methoxy-3-methylphenyl)sulfonyl]-5,6-dihydrophenanthridine as a colorless, crystalline, solid, which was characterized by LCMS (ES+, FA, CV=5) and 1H NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06894061B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-153821531fad4615bdbcd4b432500841 |
| Source note | uspto-grants-2005_05 |