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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2182037Generated: November 1, 2026

2-Bromo-4-fluorophenol → 2-Bromo-4-fluoro-1-prop-2-ynyloxybenzene

https://huagongshe.com/reaction/2182037

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-4-fluorophenolHCID 605472—
Reactant2,4-Difluoro-2-propynyloxybenzeneHCID 67047764—
Product2-Bromo-4-fluoro-1-prop-2-ynyloxybenzeneHCID 22482868—

Reaction Steps

This compound was prepared analogously to 2,4-difluoro-2-prop-ynyloxy-benzene but using 2-bromo-4-fluoro-phenol (15 g, 78 mmol) to give 2-bromo-4-fluoro-1-prop-2-ynyloxy-benzene 15. g (84%). 29g) 1,3-difluoro-5-prop-2-ynyloxy-benzene

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06894177B2
Source datasetuspto-grants-2005_05
ORD IDord-0f1c275caf704dd6930138da17b01def
Source noteuspto-grants-2005_05