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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2182038Generated: November 1, 2026

3,5-Difluorophenol → 1,3-Difluoro-5-(prop-2-yn-1-yloxy)benzene

https://huagongshe.com/reaction/2182038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorophenolHCID 75928—
Reactant2,4-Difluoro-2-propynyloxybenzeneHCID 67047764—
Product1,3-Difluoro-5-(prop-2-yn-1-yloxy)benzeneHCID 2248285067%

Reaction Steps

This compound was prepared analogously to 2,4-difluoro-2-propynyloxybenzene but using 3,5-difluoro-phenol (14 g, 107 mmol) to give 1,3-difluoro-5-prop-2-ynyloxy-benzene 12 g (67%). 9h) 8-Bromo-6-fluoro-2H-chromene

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06894177B2
Source datasetuspto-grants-2005_05
ORD IDord-f2c9b9d872404a7e86134b0ce234285d
Source noteuspto-grants-2005_05