Phenyl isocyanate → HCID 10407969, compound

Participants

Reaction Steps

Using the general method of Example 143, 1-(4-aminobutyl)-2-methyl-1H-imidazo[4,5-c]quinolin-4-amine (500 mg, 1.9 mmol) was reacted with phenyl isocyanate to provide 123 mg of N-[4-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-N′-phenylurea as a light brown solid, m.p. 171.5-172.5° C. Analysis: Calculated for C22H24N6O.0.60H2O: % C, 66.18; % H, 6.36; % N, 21.05. Found: % C, 66.05; % H, 6.43 % N, 20.61.

Provenance & Evidence