Cyclohexyl isocyanate → HCID 10410107, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(3-aminopropyl)-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine (1.50 g, 5.01 mmol) was reacted with cyclohexyl isocyanate (780 mg, 5.51 mmol) to provide 1.02 g of N-{3-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propyl}-N′-cyclohexylurea as a solid, m.p. 179-180° C. Analysis: Calculated for C23H32N6O2.0.75 H2O: % C, 63.06; % H, 7.71; % N, 19.18. Found: % C, 62.74; % H, 7.57; % N, 19.16.

Provenance & Evidence