Phenyl isocyanate → HCID 10095008, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(4-aminobutyl)-2-pentyl-1H-imidazo[4,5-c]quinolin-4-amine (800 mg, 2.5 mmol) was reacted with phenyl isocyanate (0.26 mL, 2.5 mmol) to provide 299 mg of N-[4-(4-amino-2-pentyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-N′-phenylurea as an off white solid, m.p. 159.0-160.4° C. Analysis: Calculated for C26H32N6O2.1.0 H2O: % C, 67.51; % H, 7.41; % N, 18.17. Found: % C, 67.73; % H, 7.33; % N, 17.97.

Provenance & Evidence