Ethyl 2-(4-bromophenyl)-2-methylpropanoate → alpha,alpha-Dimethyl-4-phenoxybenzeneacetic acid

HRID 218238Notes

Reaction equation

HRID 218238 reaction equation
[CH3:1][C:2]([C:8]1[CH:13]=[CH:12][C:11]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:10][CH:9]=1)([CH3:7])[C:3]([O:5]C)=[O:4].BrC1C=CC(C(C)(C)C(OCC)=O)=CC=1>>[CH3:7][C:2]([C:8]1[CH:13]=[CH:12][C:11]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:10][CH:9]=1)([CH3:1])[C:3]([OH:5])=[O:4]

Participants

3

Reactant 2

HCID 11277257Ethyl 2-(4-bromophenyl)-2-methylpropanoateHCID 21099807Methyl 2-methyl-2-(4-phenoxyphenyl)propanoate

Product 1

HCID 21099717alpha,alpha-Dimethyl-4-phenoxybenzeneacetic acid

Procedure

The title compound was prepared according to the method of Example 22B, substituting the product of Example 48B for the product of Example 22A.

Sources & evidence

ORD record
ord-a5421de64ade454db00b22c95cb3f525
Source dataset
uspto-grants-2012_06
Patent number
US08198331B2

Reaction notes

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