Ethyl 2-(4-bromophenyl)-2-methylpropanoate → 2-(1-Benzothiophen-3-yl)-2-methylpropanoic acid

HRID 218239Notes

Reaction equation

HRID 218239 reaction equation
[S:1]1[CH:5]=[C:4]([C:6]([CH3:12])([CH3:11])[C:7]([O:9]C)=[O:8])[C:3]2[CH:13]=[CH:14][CH:15]=[CH:16][C:2]1=2.BrC1C=CC(C(C)(C)C(OCC)=O)=CC=1>>[S:1]1[CH:5]=[C:4]([C:6]([CH3:12])([CH3:11])[C:7]([OH:9])=[O:8])[C:3]2[CH:13]=[CH:14][CH:15]=[CH:16][C:2]1=2

Participants

3

Reactant 2

HCID 11277257Ethyl 2-(4-bromophenyl)-2-methylpropanoateHCID 21099806Methyl 2-(benzo[b]thiophen-3-yl)-2-methylpropanoate

Product 1

HCID 210997132-(1-Benzothiophen-3-yl)-2-methylpropanoic acid

Procedure

The title compound was prepared according to the method of Example 22B substituting the product of Example 49B for the product of Example 22A.

Sources & evidence

ORD record
ord-821b9675c44f45b5ae0cb9956b11309b
Source dataset
uspto-grants-2012_06
Patent number
US08198331B2

Reaction notes

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