HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 9798977, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | HCID 9884037 | HCID 9884037 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Methylenechloride Hexane | HCID 21226440 | — |
| Product | HCID 9798977 | HCID 9798977 | 46% |
Reaction Steps
0.8 g (2.4 mmol) of 3-(5-carboxy-2-furyl)-1-(2-phenylethyl)indazole were admixed with 25 ml of ethanol, 150 ml of toluene and 2 ml of conc. sulfuric acid and heated on a water separator for 3 h. Silica gel chromatography using dichloromethane/hexane (2:1) of the residue that was obtained after concentration using a rotary evaporator gave 400 mg (46%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06897232B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-838b5821505b4ceeba109736edd61dc0 |
| Source note | uspto-grants-2005_05 |