Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Fluoride → HCID 10407453, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Fluoride | HCID 522689 | — |
| 반응물 | 4-Bromo-6-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]-1,2-di(tert-butyldimethylsilyloxy)benzene | HCID 60130672 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | tert-Butyl methyl ether | HCID 15413 | — |
| 용매 | N,N-dimethylformamide methanol | HCID 21901440 | — |
| 생성물 | HCID 10407453 | HCID 10407453 | — |
반응 단계
To a solution of 20 (0.19 g, 0.32 mmol) in methanol:dimethylformamide 1:1 (4 mL), acetic acid was added (0.114 mL, 1.9 mmol) followed by potassium fluoride (0.110 mg, 1.9 mmol). The mixture was stirred for 30 hours then diluted with tertbutylmethyl ether (50 mL) and washed with water (20 mL) then brine (20 mL), then dried over sodium sulphate. The solvent was removed under reduced pressure to give a crude which was purified by column (cyclohexane:AcOEt 7:3+1% AcOH) to give 0.097 g of ZSB-74:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08198302B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-1893776e350a4ca2bfce44fb5ee61421 |
| 출처 메모 | uspto-grants-2012_06 |