HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 69214809, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester | HCID 17453 | — |
| Reactant | HCID 22479142 | HCID 22479142 | — |
| Product | HCID 69214809 | HCID 69214809 | — |
Reaction Steps
A mixture of 6-[4-(2-formylphenyl)benzyl]-8-(3,5-dichlorophenyl)-1,8-diazabicyclo(4.3.0]nonane-7,9-dione (0.205 g) and methyl (triphenylphosphoranylidene)acetate (0.223 g) in toluene (5 mL) was refluxed for 8 hours. The mixture was evaporated and the residue was purified by chromatography (Silica gel: EtOAc/hexane: 1/4 to 1/3, Chromatotron) to afford the titled compound (0.229 g). MS (m/z) 571(M++Na).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06897225B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-6e2687618a074446b9a327dd33e35f0a |
| Source note | uspto-grants-2005_05 |