HCID 21948934, compound → 4-Methyl-2-oxo-4-phenylpentanoic acid

HRID 2182651Notes

Reaction equation

HRID 2182651 reaction equation
O1[C:5]2[CH:6]=[CH:7][CH:8]=[C:9]([C:10]([CH3:28])([CH3:27])[CH2:11][C:12](=[O:26])[C:13](NC3C=CC=C4C=3C=CC=N4)=[O:14])[C:4]=2OC1.CC(C1C=CC=CC=1)(C)CC(=O)C(N)=[O:34]>>[CH3:27][C:10]([C:9]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1)([CH3:28])[CH2:11][C:12](=[O:26])[C:13]([OH:14])=[O:34]

Participants

3

Reactant 2

HCID 21948934HCID 21948934, compoundHCID 86592875HCID 86592875, compound

Product 1

HCID 112411954-Methyl-2-oxo-4-phenylpentanoic acid

Procedure

According to the instructions for 4-(1,3-benzodioxol-4-yl)-N-(quinolin-5-yl)-4-methyl-2-oxopentanamide (Example 12) after chromatography on silica gel, 370 mg of N-(quinolin-5-yl)-)-4-methyl-2-oxo-4-phenylpentanamide is obtained from 515 mg of 4-methyl-2-oxo-4-phenylpentanoic acid (WO98/54159). Flash point: 98-99° C.

Sources & evidence

ORD record
ord-cffebbecadc8449aa079004edcb8dae7
Source dataset
uspto-grants-2005_05
Patent number
US06897224B2

Reaction notes

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