HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-Methoxy-5-nitroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | o-Toluenesulfonyl chloride | HCID 8623 | — |
| Reactant | 5-Nitroquinoline 1-oxide | HCID 82085 | — |
| Product | 2-Methoxy-5-nitroquinoline | HCID 21948893 | — |
Reaction Steps
A suspension of 1 g (5 mmol) of 5-nitroquinoline-1-oxide, 1.23 g (6.4 mmol) of toluenesulfonic acid chloride and 1.4 ml (9.9 mmol) of triethylamine in 30 ml of MeOH is stirred for 20 hours at room temperature. The solid is suctioned off and washed with MeOH: 565 mg of light yellow product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06897224B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-b21cb9ea2a0b430a9c9aa5f06bcb1a19 |
| Source note | uspto-grants-2005_05 |