4-Chlorobenzoyl chloride → HCID 10193724, compound

Participants

Reaction Steps

Following the protocol of Example 8 and employing (6-chloropyridin-3-yl)-(1-methyl-1H-pyrrol-2-yl)methanone hydrochloride in place of (1-methyl-1H-pyrrol-2-yl)-pyridin-3-ylmethanone hydrochloride and 4-chlorobenzoyl chloride in place of 4-fluorobenzoyl chloride, the title compound was obtained and recrystallized from MTBE: mp 150-152° C. ES-MS m/z=360 (M++H). 1H NMR (300 MHz, CDCl3) δ 4.1 (s, 3H); 7.2 (s, 1H); 7.5 (m, 3H); 7.56 (s, 1H); 7.8 (dd, 2H); 8.05 (d, 1H); 8.8 (s, 1H). Anal calc'd for C18H12C2N2O2: 60.19; H, 3.37; N, 7.8. Found: C, 59.9; H, 3.34; N, 7.71.

Provenance & Evidence