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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2182984Generated: October 30, 2026

Trifluoroacetic acid → HCID 59909761, compound

https://huagongshe.com/reaction/2182984

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59909849HCID 59909849—
SolventDichloromethaneHCID 6344—
ProductHCID 59909761HCID 5990976193.1%

Reaction Steps

A solution of tert-butyl (3R)-6-cyclohexyl-3-[3-(4-morpholinylcarbonyl)-1,2,4-oxadiazol-5-yl]hexanoate (Preparation 21) (269 mg, 0.62 mmol) in dichloromethane (4 ml) was treated with trifluoroacetic acid (1 ml) and the resulting mixture was stirred at room temperature under a nitrogen atmosphere for 17 hours. The solvent was removed under reduced pressure and the residue azeotroped from toluene to afford the title compound (219 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06897306B2
Source datasetuspto-grants-2005_05
ORD IDord-6ea4d9260e9544e3a1d1fd979de0530b
Source noteuspto-grants-2005_05