HCID 131724919, compound → HCID 178522010, compound

Participants

Reaction Steps

Cyclopentyl-N-(3-{1-perhydro-2H-pyran-2-yl-5-[1-(triphenylmethyl)(1,2,4-triazol-3-yl)](1H-indazol-3-yl)}phenyl)carboxamide was dissolved in 4 mL of 4.0 N HCl in 1,4-dioxane and the reaction was stirred at room temperature overnight. After neutralization with aqueous NaHCO3, the reaction mixture was evaporated to dryness and purified by preparative HPLC. (0.043 g, 46% yield over 2 steps): 1H NMR (CD3OD) δ 8.73 (s, 1H), 8.36 (br s, 1H), 8.17 (s, 1H), 8.10 (d, 1H), 7.76-7.67 (m, 3H), 7.5 (t, 1H), 2.85 (quintet, 1H), 2.04-1.63 (m, 8H); ES-MS (m/z) 373.

Provenance & Evidence