HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218344Generated: October 29, 2026
Hydrochloric Acid → Moxifloxacin hydrochloride
https://huagongshe.com/reaction/218344
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Moxifloxacin | HCID 152946 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Moxifloxacin hydrochloride | HCID 101526 | 105% |
Reaction Steps
Moxifloxacin base 50.0 g was stirred in 200.0 ml methanol for 10-15 minutes at 25-3-° C. The pH was adjusted to 1.0-2.0 using methanolic hydrochloric acid. The reaction mass was chilled to 0-5° C. and maintained for 1 hour. The solids were filtered and dried under vacuum at 85-90° C. to yield 52.5 g (105%) of moxifloxacin hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08198451B2 |
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| Source dataset | uspto-grants-2012_06 |
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| ORD ID | ord-a3cdaec056af441abb5560ca037053ad |
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| Source note | uspto-grants-2012_06 |
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