HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 22472958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 22472956 | HCID 22472956 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22472958 | HCID 22472958 | 96.7% |
Reaction Steps
To a solution of 4-[5-(5-Nitro-pyridin-2-yloxy)-indazol-1-yl]-benzonitrile (0.79 mmol) in 10 mL of methanol was added 10 mL of ethyl acetate and 30 mg of platinum (IV) oxide. After shaking under 50 psi of H2 for 3 h, the mixture was filtered through a pad of Celite and concentrated in vacuo, affording 0.25 g of 4-[5-(5-Amino-pyridin-2-yloxy)-indazol-1-yl]-benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06900201B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-301369d2c3ca4309a7777f1ad2ed06e9 |
| Source note | uspto-grants-2005_05 |