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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2183732Generated: October 31, 2026

Ethyl Acetate → HCID 22472958, compound

https://huagongshe.com/reaction/2183732

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantHCID 22472956HCID 22472956—
CatalystAdams' catalystHCID 345198—
SolventMethanolHCID 887—
ProductHCID 22472958HCID 2247295896.7%

Reaction Steps

To a solution of 4-[5-(5-Nitro-pyridin-2-yloxy)-indazol-1-yl]-benzonitrile (0.79 mmol) in 10 mL of methanol was added 10 mL of ethyl acetate and 30 mg of platinum (IV) oxide. After shaking under 50 psi of H2 for 3 h, the mixture was filtered through a pad of Celite and concentrated in vacuo, affording 0.25 g of 4-[5-(5-Amino-pyridin-2-yloxy)-indazol-1-yl]-benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900201B2
Source datasetuspto-grants-2005_05
ORD IDord-301369d2c3ca4309a7777f1ad2ed06e9
Source noteuspto-grants-2005_05