[3-(2,5-Dichlorophenoxy)pentyl]methylcarbamic acid, 1,1-dimethylethyl ester → 3-(2,5-Dichlorophenoxy)-n-methyl-1-pentanamine hydrochloride

Participants

Reaction Steps

[3-(2,5-Dichlorophenoxy)pentyl]methylcarbamic acid, 1,1-dimethylethyl ester (180 mg, 0.487 mmol) was dissolved in 4M hydrogen chloride in dioxane (6 ml). The resulting solution was stirred at room temperature for 3 h, then the solvent was evaporated. The residue was recrystallised from diethyl ether/ethanol to give 130 mg (88%) of the title compound as a white solid.

Provenance & Evidence