4-Chloro-2-fluorobenzonitrile → HCID 90729204, compound

HRID 2183842Notes

Reaction equation

HRID 2183842 reaction equation
[OH:1][CH:2]([CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[CH2:3][CH2:4][N:5]([CH3:13])[C:6](=[O:12])[O:7][C:8]([CH3:11])([CH3:10])[CH3:9].[Cl:21][C:22]1[CH:29]=[CH:28][C:25]([C:26]#[N:27])=[C:24](F)[CH:23]=1>>[Cl:21][C:22]1[CH:23]=[CH:24][C:25]([C:26]#[N:27])=[C:28]([CH:29]=1)[O:1][CH:2]([CH2:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[CH2:3][CH2:4][N:5]([CH3:13])[C:6](=[O:12])[O:7][C:8]([CH3:11])([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 936554-Chloro-2-fluorobenzonitrileHCID 69745256HCID 69745256, compound

Product 1

HCID 90729204HCID 90729204, compound

Procedure

The title compound was prepared according to the method of Example 3 step (b) but using (3-hydroxy-4-phenylbutyl)methylcarbamic acid, 1,1-dimethylethyl ester, and 4-chloro-2-fluorobenzonitrile.

Sources & evidence

ORD record
ord-ced7e707c4554a7383f8ed4340174443
Source dataset
uspto-grants-2005_05
Patent number
US06900243B2

Reaction notes

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